Sources tell WWL-TV police fired shots as the suspects came towards them in a vehicle. One person is in custody. No injuries were reported.
The officer called for assistance and a perimeter was set up in the the 6400-6500 block of Louis XIV to Louisville streets in between Milne Boulevard and Canal Boulevard in response.
Canal Boulevard at Harrison Avenue is also blocked.
"Four schools in the area have been placed on lockdown – Mt. Carmel Academy, Hynes Academy, St. Dominic and St. Paul schools," NOPD officials said.
The public is asked to avoid the area.
Reports of police responding to Lakeview with rifles drawn started around 9 a.m.